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Innovations galenic The pharmaceutical industry is continually developing new ways of bringing the drug to their destination as quickly and efficiently. Like the discovery of new drugs, new galenic are subject to patent ownership, going after a time into the public domain. For example, Norman Leo Henderson and Louis Nasir elow invented in 1969 extended-release capsules patent 3,427,378. Thus, systems are continually being invented, that based on the galenic formulas classic provides more effectiveness to the commercial product. Examples include: OROS system or osmotic micropump. It is a system that allows controlled release of the drug temporarily. It comprises a reservoir containing the drug, consisting of a solid core with osmotic capacity. Surrounding the reservoir there is a semipermeable membrane that allows water to pass from outside the system.When the tablet comes in contact with gastrointestinal juice, water penetration causes the dissolution of the osmotic core and drug exit through a hole or area of release. The pore size semipermeable membrane will condition the degree of water entry and therefore the rate of release of active ingredient. Filmtab System. MUPS system: In 1998, AstraZeneca developed the system MUPS (Multiple Unit Pellet System) or Multigranular System. The MUPS tablet formulation allows rapid release of 1,000 to 2,000 active units with protection from stomach acid. They are smaller than the units contained in a traditional dish, easily dispersed and dissolved in the intestine delgadoofreciendo more predictable efficacy . Liposomes: Liposomes are small vesicles composed mainly extraordinarily organized phospholipid bilayers.These vesicles contain an internal aqueous phase and are suspended in an external aqueous phase. Are basically used to transport the active ingredients in a selective manner as possible. Depending on their nature, the drug can be incorporated within the liposome (if hydrophilic) or the liposomal bilayer (the case of lipophilic). The advantages of this dosage form are: Increased efficiency and reduced toxicity encapsulation of the active ingredient. Prolongation of the effect. Better absorption, penetration and diffusion. Possible alternative routes of administration. Stabilization of the asset. Flas System "is a solid oral form which has the property that do not have to swallow the contents, but is absorbed directly into contact with the oral cavity Chronosph re System.Gel Termoreversible: a pharmaceutical form which allows the preparation is maintained in the form of a liquid at temperatures below 25 C, in contrast to temperatures near 35 degrees C (when in contact with the human body) increases its viscosity and the liquid is transforms into a gel. Ideal for use on mucous membranes because the liquid form but favors the penetration into solid prevent dripping and swallowing. SALVAT Spanish laboratories using this system for some of its products use nasally.